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MYP_054790
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Basic Information
FP4
Antimicrobial
Antiviral
Antiviral ▸ Anti-Influenza virus ▸ Anti-Influenza A ▸ Anti-Influenza A virus
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor
Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition
Standard
16 amino acids
C117H166N28O18
Standard
Sequence
RRKKWLVFFVIFYFFR
Physicochemical Analysis
2252.75 Da
11.73
4.76
4.55
0.2973
0.45
0.37
0.06
73.26
85.00
0.4375
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
773.58
2.01
30.0
23.0
71.0
163.0
8.0
15.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0171336 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-Influenza A virus Fusion inhibition
Influenza A virus PR8/Eng09 (H1N1) | MDCK cells
0.0778 μM
IC50
Mammalian: 1 h; Yeast: 2 min; E. coli: 2 min
PaperA novel family of peptides with potent activity against influenza A viruses. | Nicol MQ, Ligertwood Y, Bacon MN, Dutia BM, Nash AA. | J Gen Virol. 2012 May;93(Pt 5):980-986. | DOI:10.1099/vir.0.038679-0 | PMID:22258859 PMID22258859 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22258859/
RECORD: Rec_0201835 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-Influenza A virus Fusion inhibition
Influenza A virus A/WSN/33 H1N1 | MDCK cells
4e-05 μM
IC50
Mammalian: 1 h; Yeast: 2 min; E. coli: 2 min
PaperA novel family of peptides with potent activity against influenza A viruses. | Nicol MQ, Ligertwood Y, Bacon MN, Dutia BM, Nash AA. | J Gen Virol. 2012 May;93(Pt 5):980-986. | DOI:10.1099/vir.0.038679-0 | PMID:22258859 PMID22258859 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22258859/
RECORD: Rec_0339358 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-Influenza A virus Fusion inhibition
Influenza A virus PR8/Vic (H3N2) | MDCK cells
0.0535 μM
IC50
Mammalian: 1 h; Yeast: 2 min; E. coli: 2 min
PaperA novel family of peptides with potent activity against influenza A viruses. | Nicol MQ, Ligertwood Y, Bacon MN, Dutia BM, Nash AA. | J Gen Virol. 2012 May;93(Pt 5):980-986. | DOI:10.1099/vir.0.038679-0 | PMID:22258859 PMID22258859 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22258859/
RECORD: Rec_0372353 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
influenza A virus A/WSN/33 H1N1:inhibition of viral replication in MDCK cells
0.00004 μM
IC50
PaperPubMed PMID: 22258859 PMID22258859 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22258859/
RECORD: Rec_0385871 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
influenza A virus PR8/Viet (H5N1):inhibition of viral replication in MDCK cells
0.1325 μM
IC50
PaperPubMed PMID: 22258859 PMID22258859 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22258859/
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