Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length404 amino acids

Chemical FormulaC2034H3209N521O572S17

DescriptionStandard

        MLKTWYFVLLCWLSLRLEANPGLKVRITQKGLDYGMRQSEVKVMTKNFPSYPHCRRIGMELVKQAVLKETFPSWSGQESLSVVKVNYVISRLRINAVDFPETSASFIPGTGICLSVAQASATISADWRMNAWLLKGKGEITVSISGLFISIIFNVSRDSTGHLSTLLHNCQLSIGSVKVKLSGRSSWIYSFLSGYLEKPIHTKLDKNLCLNIKYKIQMMDAQLRKHKVLSQIDTFAQVDYSLLSSPAVFKSHINLDLKGTVYPVGNHTDPPFMPAPFALPNQGDSMIYLGVSNYFLKSASLAYYRAGAFNITISEELATTFSLNTSLLKYFVSETSLSQAAACPVLLNLMATLPPAVSLNADRCVLQITGSVEVFAALPNSTTQYIFTGNLVPVLPTALQSWLP
    

Molecular Weight44658.49 Da

Isoelectric Point (pI)9.30

Net Charge (pH 7.0)12.05

Net Charge (pH 7.4) 11.29

Charge Density (pH 7.0) 0.0298

GRAVY Index0.18

Hydrophobic Moment 0.63

Boman Index0.16

Instability Index36.09

Aliphatic Index 101.83

Aromaticity 0.0990

Extinction Coeff. Reduced 60850.00

Extinction Coeff. Oxidized 61225.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0219345 VERIFIED: NO

Provenance & Taxonomy

OrganismPipra filicauda [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria