Peptide Database

Peptide NamehP6

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Anti-angiogenic

Standard StatusStandard

Sequence Length24 amino acids

Chemical FormulaC126H183N39O37

DescriptionStandard

        HPTWPQKSVWHGSDPNGRRLTESY
    

Molecular Weight2836.04 Da

Isoelectric Point (pI)8.60

Net Charge (pH 7.0)0.94

Net Charge (pH 7.4) 0.63

Charge Density (pH 7.0) 0.0390

GRAVY Index-1.57

Hydrophobic Moment 0.47

Boman Index-0.25

Instability Index49.35

Aliphatic Index 28.33

Aromaticity 0.1250

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1227.17

LogP -13.77

H-bond Donors 43.0

H-bond Acceptors 40.0

Rotatable Bonds 84.0

Heavy Atoms 202.0

Ring Count 10.0

Amide Bonds 25.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0291847 VERIFIED: YES

Provenance & Taxonomy

OrganismHuman endostatin [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer Cytotoxic

RECORD: Rec_0360735 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]