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MYP_054703
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Basic Information
hP6
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Anti-angiogenic
Standard
24 amino acids
C126H183N39O37
Standard
Sequence
HPTWPQKSVWHGSDPNGRRLTESY
Physicochemical Analysis
2836.04 Da
8.60
0.94
0.63
0.0390
-1.57
0.47
-0.25
49.35
28.33
0.1250
12490.00
12490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1227.17
-13.77
43.0
40.0
84.0
202.0
10.0
25.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0010638 VERIFIED: YES
Provenance & Taxonomy
Human endostatin [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
BxPC-3 (No inhibition at 7 mg/kg/d)
PaperPubMed PMID: 15867360 PMID15867360 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15867360/
RECORD: Rec_0180078 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAntiCP 2.0: an updated model for predicting anticancer peptides (benchmark provenance; exact sequence-level experiment paper unresolved here) | https://pubmed.ncbi.nlm.nih.gov/32770192/
RECORD: Rec_0252961 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Endostatin-derived peptide
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Anti-angiogenic Cytotoxic
BxPC-3
7 mg/kg/d
Inhibition
PMID15867360 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15867360/
RECORD: Rec_0257719 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PMID15867360 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15867360/
RECORD: Rec_0280796 VERIFIED: YES
Provenance & Taxonomy
Human endostatin [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PaperPubMed PMID: 15867360 PMID15867360 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15867360/
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