Peptide Database

Peptide NameNeurotensin

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length13 amino acids

Chemical FormulaC69H118N20O18

DescriptionStandard

        EAIVSKARRPYIL
    

Molecular Weight1515.80 Da

Isoelectric Point (pI)9.99

Net Charge (pH 7.0)1.83

Net Charge (pH 7.4) 1.66

Charge Density (pH 7.0) 0.1411

GRAVY Index0.04

Hydrophobic Moment 0.52

Boman Index-0.07

Instability Index76.39

Aliphatic Index 127.69

Aromaticity 0.0769

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 631.31

LogP -3.98

H-bond Donors 23.0

H-bond Acceptors 20.0

Rotatable Bonds 49.0

Heavy Atoms 107.0

Ring Count 2.0

Amide Bonds 12.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0036017 VERIFIED: YES

Provenance & Taxonomy

OrganismBufo marinus [Animal]

FamilyNeurotensin

Tax ID8386

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermPyroglutamate

Bio-Activity Profile

Function

Neuropeptide Hormone

RECORD: Rec_0119917 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0412786 VERIFIED: YES

Provenance & Taxonomy

OrganismRhinella marina [Animal]

FamilyNeurotensin

Tax ID8386

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Bio-Activity Profile

Function

-

Half-LifeMammalian: 1 hour; Yeast: 30 min; E. coli: >10 hour