Peptide Database

Peptide NamePen10

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length10 amino acids

Chemical FormulaC64H104N22O13S

DescriptionStandard

        FQNRRMKWKK
    

Molecular Weight1421.72 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)4.76

Net Charge (pH 7.4) 4.55

Charge Density (pH 7.0) 0.4757

GRAVY Index-2.39

Hydrophobic Moment 0.11

Boman Index-0.85

Instability Index66.28

Aliphatic Index 0.00

Aromaticity 0.2000

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 629.05

LogP -4.46

H-bond Donors 23.0

H-bond Acceptors 19.0

Rotatable Bonds 51.0

Heavy Atoms 100.0

Ring Count 3.0

Amide Bonds 11.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0362532 VERIFIED: YES

Provenance & Taxonomy

OrganismDrosophila melanogaster [Animal]

FamilyPenetratin

Tax ID7227

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermBiotinylation

C-TermAmidation

Other ModsN-term detail: Labeled with Biotinyl-bAla

Bio-Activity Profile

Function

Cell-penetrating peptide

TargetHaCat/ A549 cells

MethodCellular uptake assay

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