Peptide Database

Peptide NamePancreatic hormone

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Neuropeptide Y family

Standard StatusStandard

Sequence Length36 amino acids

Chemical FormulaC192H275N51O59

DescriptionStandard

        APSEPHHPGDQATQDQLAQYYSDLYQYITFVTRPRF
    

Molecular Weight4241.54 Da

Isoelectric Point (pI)5.26

Net Charge (pH 7.0)-2.03

Net Charge (pH 7.4) -2.33

Charge Density (pH 7.0) -0.0563

GRAVY Index-0.98

Hydrophobic Moment 0.56

Boman Index-0.09

Instability Index37.14

Aliphatic Index 48.89

Aromaticity 0.1667

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 5960.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1774.54

LogP -17.64

H-bond Donors 59.0

H-bond Acceptors 59.0

Rotatable Bonds 127.0

Heavy Atoms 302.0

Ring Count 12.0

Amide Bonds 40.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0030595 VERIFIED: YES

Provenance & Taxonomy

OrganismRana temporaria [Animal]

FamilyPancreatic hormone

Tax ID8407

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Hormone Endocrine

Half-LifeMammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0093473 VERIFIED: NO

Provenance & Taxonomy

OrganismRana temporaria [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Hormone

RECORD: Rec_0173534 VERIFIED: YES

Provenance & Taxonomy

OrganismRana temporaria [Animal]

FamilyNPY

Tax ID8407

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

NPY-family Neuropeptide Neuromodulator

RECORD: Rec_0234333 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/