Peptide Database

Peptide NameGlial cell line-derived neurotrophic factor

Function Ontology

Immunology ▸ Immune modulation ▸ Cytokine modulation

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Standard StatusStandard

Sequence Length134 amino acids

Chemical FormulaC640H1053N209O196S8

DescriptionStandard

        SPDKQMAVLPRRERNRQAAAANPENSRGKGRRGQRGKNRGCVLTAIHLNVTDLGLGYETKEELIFRYCSGSCDAAETTYDKILKNLSRNRRLVSDKVGQACCRPIAFDDDLSFLDDNLVYHILRKHSAKRCGCI
    

Molecular Weight15068.01 Da

Isoelectric Point (pI)9.44

Net Charge (pH 7.0)8.67

Net Charge (pH 7.4) 8.17

Charge Density (pH 7.0) 0.0647

GRAVY Index-0.68

Hydrophobic Moment 0.78

Boman Index-0.24

Instability Index49.45

Aliphatic Index 76.49

Aromaticity 0.0522

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6666.87

LogP -78.86

H-bond Donors 243.0

H-bond Acceptors 216.0

Rotatable Bonds 516.0

Heavy Atoms 1053.0

Ring Count 14.0

Amide Bonds 145.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0342601 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyTGF-beta family

Tax ID9606; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide41-102; 68-131; 72-133

Bio-Activity Profile

Function

Cytokine Growth factor TGF-beta family