‹ ›
MYP_054540
← PREVIOUS NEXT → BACK
Basic Information
Ano-D4,7-7C4
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
not Standard
10 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
GLLKRIXTLL
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0203305 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 7
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa ATCC 27853
4 μM
MIC
PMID32654770 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32654770/
RECORD: Rec_0209460 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D or modified amino-acid peptide [Mixed]
None
Amidation
x=D-Lys-C12 (D-Lysine with laurylated side group); k=D-Lys
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
mouse erythrocytes
32 μM
10% Hemolysis
PaperAntimicrobial peptides conjugated with fatty acids on the side chain of D-amino acid promises antimicrobial potency against multidrug-resistant bacteria. Eur J Pharm Sci. 2020 Jan 1;141:105123. doi: 10.1016/j.ejps.2019.105123. PMID: 31676352. PMID31676352 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31676352/
RECORD: Rec_0216461 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 7
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus MR
2-4 μM
MIC
PMID32654770 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32654770/
RECORD: Rec_0219814 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 7
Bio-Activity Profile
Antimicrobial Antibacterial
Acinetobacter baumanniii ATCC 19606
128 μM
MIC
PMID32654770 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32654770/
RECORD: Rec_0222349 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 7
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa ATCC 9027
64 μM
MIC
PMID32654770 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32654770/
FIRST PREV 1 ... 8 9 10 11 12 ... 20 NEXT LAST
Showing 5 records · Page 10 of 20