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MYP_054516
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ Inhibitor
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
12 amino acids
C56H94N14O16
Standard
Sequence
LAPSLPGKPKPD
Physicochemical Analysis
1219.43 Da
8.59
0.76
0.55
0.0635
-0.79
0.19
-0.03
31.39
73.33
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
457.83
-3.78
13.0
17.0
34.0
86.0
4.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0055795 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Inhibitor
1065.6
PaperZambrowicz A., Eckert E., Pokora M., Bobak ?., D?browska A., Szo?tysik M., Trziszka T., Chrzanowska J.. Antioxidant and antidiabetic activities of peptides isolated from a hydrolysate of an egg-yolk protein by-product prepared with a proteinase from Asian pumpkin (Cucurbita ficifolia). RSC Adv. 5, 10460-10467.
RECORD: Rec_0092969 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antioxidant
PaperZambrowicz A., Eckert E., Pokora M., Bobak ?., D?browska A., Szo?tysik M., Trziszka T., Chrzanowska J.. Antioxidant and antidiabetic activities of peptides isolated from a hydrolysate of an egg-yolk protein by-product prepared with a proteinase from Asian pumpkin (Cucurbita ficifolia). RSC Adv. 5, 10460-10467, 2015.
RECORD: Rec_0202051 VERIFIED: YES
Provenance & Taxonomy
Gallus gallus [Animal]
9031.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
1.97
PaperEckert E., Zambrowicz A., Pokora M., Setner B., D?browska A., Szo?tysik M., Szewczuk Z., Polanowski A., Trziszka T., Chrzanowska J.. Egg-yolk protein by-product as a source of ACE-inhibitory peptides obtained with using unconventional proteinase from Asian pumpkin (Cucurbita ficifolia). Journal of Proteomics 110, 107-116, 2014.
RECORD: Rec_0280113 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antidiabetic DPP-IV inhibitory
Dipeptidyl peptidase IV
361.5
PaperZambrowicz A., Eckert E., Pokora M., Bobak ?., D?browska A., Szo?tysik M., Trziszka T., Chrzanowska J.. Antioxidant and antidiabetic activities of peptides isolated from a hydrolysate of an egg-yolk protein by-product prepared with a proteinase from Asian pumpkin (Cucurbita ficifolia). RSC Adv. 5, 10460-10467, 2015.
RECORD: Rec_0304632 VERIFIED: YES
Provenance & Taxonomy
Gallus gallus [Animal]
Angiotensin
9031
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory
Angiotensin-converting enzyme
1.97 μM
IC50