Peptide Database

Peptide NameBrevinin-2-OA1

Function Ontology

Antimicrobial

Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor

Standard StatusStandard

Sequence Length33 amino acids

Chemical FormulaC147H254N40O45S2

DescriptionStandard

        GILDTLKEFGKAAAKGVAQTLLNTASCKLAKTC
    

Molecular Weight3365.96 Da

Isoelectric Point (pI)9.24

Net Charge (pH 7.0)2.74

Net Charge (pH 7.4) 2.50

Charge Density (pH 7.0) 0.0830

GRAVY Index0.24

Hydrophobic Moment 0.66

Boman Index0.11

Instability Index5.42

Aliphatic Index 97.88

Aromaticity 0.0303

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1386.55

LogP -15.40

H-bond Donors 50.0

H-bond Acceptors 50.0

Rotatable Bonds 117.0

Heavy Atoms 234.0

Ring Count 1.0

Amide Bonds 34.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0166417 VERIFIED: YES

Provenance & Taxonomy

OrganismAmolops wuyiensis [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)

RECORD: Rec_0333026 VERIFIED: NO