Peptide Database

Peptide NameBeta-defensin 126 (Defensin; beta 126) (Epididymal secretory protein 13.2) (ESP13.2)

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length123 amino acids

Chemical FormulaC572H953N157O169S13

DescriptionStandard

        MKSLLFTLAVFMLLAQLVSGNLYVKRCLNDIGICKKTCKPEEVRSEHGWVMCGKRKACCVPADKRSAYPSFCVHSKTTKTSTVTARATATTATTATAATPLMISNGLISLMTTMAATPVSPTT
    

Molecular Weight13150.48 Da

Isoelectric Point (pI)9.60

Net Charge (pH 7.0)9.60

Net Charge (pH 7.4) 9.16

Charge Density (pH 7.0) 0.0781

GRAVY Index0.20

Hydrophobic Moment 0.55

Boman Index0.09

Instability Index38.81

Aliphatic Index 80.16

Aromaticity 0.0488

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5189.62

LogP -58.88

H-bond Donors 193.0

H-bond Acceptors 194.0

Rotatable Bonds 430.0

Heavy Atoms 911.0

Ring Count 15.0

Amide Bonds 126.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0368374 VERIFIED: YES

Provenance & Taxonomy

OrganismMacaca fascicularis [Animal]

FamilyBeta-defensin; Defensin

Tax ID9541

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic