Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length421 amino acids

Chemical FormulaC2147H3311N555O618S13

DescriptionStandard

        MHDLSGSYGIGWLGSVNYVFSGMRIHRFLLQDSQLSLHPGQGIKASLSDNYISVGGNWKVEKSFITLHGTFDLSVDGISILVSLNLGKDQSGRPTVSVIHCHNSISHVSVEISGHISWILNLFHERIENNVKPILEQKICEMVRKSAISRLEPYLRTLPVTLMIDQIAGIDYSLVGAPQVTSQGLDTHFKGEFFSRNWNTSVPFDAPPITLPQKHDHMIYFAVSEYAFNTASRVYYQAGQMKFTIQNKHIPLDFPIQLHTSSFWAIIPQLAMLYPNMELELETSPESAPFLTFTPGNVTFMPVMDIQAFVLLPNSAGRKSLFQIRASTNISITINVNSTRITGSLTTGSELKLELKDSNIGFFNVNLMESIFNYYALHTVYPSLNAKLEEGIPLPLPRDTYLNSLEFQIHENFLFLGANVD
    

Molecular Weight47202.45 Da

Isoelectric Point (pI)6.04

Net Charge (pH 7.0)-7.08

Net Charge (pH 7.4) -8.22

Charge Density (pH 7.0) -0.0168

GRAVY Index0.01

Hydrophobic Moment 0.67

Boman Index0.15

Instability Index36.13

Aliphatic Index 97.46

Aromaticity 0.1045

Extinction Coeff. Reduced 48360.00

Extinction Coeff. Oxidized 48485.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0314763 VERIFIED: NO

Provenance & Taxonomy

OrganismCapra hircus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria