Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length56 amino acids

Chemical FormulaC279H440N66O84S6

DescriptionStandard

        MTNMSKFDDFDLDVVKVSKQDSKITPQVLSKSLCTPGCITGPLQTCYLCFPTFAKY
    

Molecular Weight6255.26 Da

Isoelectric Point (pI)7.62

Net Charge (pH 7.0)0.46

Net Charge (pH 7.4) 0.17

Charge Density (pH 7.0) 0.0082

GRAVY Index-0.02

Hydrophobic Moment 0.47

Boman Index0.07

Instability Index42.95

Aliphatic Index 71.25

Aromaticity 0.1071

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2406.63

LogP -23.52

H-bond Donors 85.0

H-bond Acceptors 91.0

Rotatable Bonds 203.0

Heavy Atoms 435.0

Ring Count 10.0

Amide Bonds 59.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0050839 VERIFIED: NO

Provenance & Taxonomy

OrganismBacillus subtilis [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-positive bacteria

MethodQualitative functional evidence