Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length524 amino acids

Chemical FormulaC2589H4136N676O733S20

DescriptionStandard

        MENIKDIKSGKENITSSCKVLYRSLAPLQGLQALAASENEDMAREPDSVLRWAALLVLATLGTAVMAATNPGVVARITQKGLDYACQQGVAVLQKELEKIKIPDFSGSFKIKHLGKGHYSFYSMVVRGFQLPSSQIRLVPNKGLDVSIINANMKISGKWKARKKFIKVKGNFDLSVTGISISAGLELGFDPASGLPTATCSSCSSHIDSVRVHISGGKIGWLIQLFHKKIESSIRNTMTSKICQIVTSSVSSKLQSYLKTLRVTTKIDKVAGINYSLVAPPTATADNLDGQLKGEFFSVAHPGPFPFTSPALAFPNDHDRMVYLGISDYFFNTAGFVYQQAGVLHLTITDDMIPKKSKFRLTTTFLGTLIPEVAKMFPNMMVQLNISASSPPHLTVLPTGLIFTPALEVQAFAVLPNSSLASLFVLHLSTNASMEVSATADRLVGKLSMDRLLLELKHSDIGPFSVVVLQAIMNYVLSTTVIPRINEWLMKGFPLPLPANIQLFNLVLQSHQNFLLFGADVHYS
    

Molecular Weight57101.92 Da

Isoelectric Point (pI)9.41

Net Charge (pH 7.0)14.60

Net Charge (pH 7.4) 13.55

Charge Density (pH 7.0) 0.0279

GRAVY Index0.18

Hydrophobic Moment 0.73

Boman Index0.15

Instability Index36.28

Aliphatic Index 101.97

Aromaticity 0.0802

Extinction Coeff. Reduced 38390.00

Extinction Coeff. Oxidized 38640.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0279031 VERIFIED: NO

Provenance & Taxonomy

OrganismZalophus californianus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria