Peptide Database

Peptide NameSYELPDGQVITIGNER

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ Thrombin inhibition ▸ Thrombin inhibitory

Hemostasis ▸ Anticoagulant activity

Hemostasis ▸ Antithrombotic activity

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length16 amino acids

Chemical FormulaC77H123N21O28

DescriptionStandard

        SYELPDGQVITIGNER
    

Molecular Weight1790.92 Da

Isoelectric Point (pI)4.14

Net Charge (pH 7.0)-2.53

Net Charge (pH 7.4) -2.75

Charge Density (pH 7.0) -0.1584

GRAVY Index-0.64

Hydrophobic Moment 0.22

Boman Index-0.03

Instability Index1.97

Aliphatic Index 91.25

Aromaticity 0.0625

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 811.70

LogP -8.84

H-bond Donors 27.0

H-bond Acceptors 26.0

Rotatable Bonds 58.0

Heavy Atoms 126.0

Ring Count 2.0

Amide Bonds 17.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0109016 VERIFIED: YES

Provenance & Taxonomy

OrganismWhitmania pigra [Animal]; Hirudo nipponica [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Anticoagulant Antithrombotic Enzyme inhibitory Thrombin inhibitory

Targetthrombin

Activity255.75 μM

MethodIC50

RECORD: Rec_0397079 VERIFIED: YES