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MYP_054451
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Basic Information
LL-III/34
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
15 amino acids
C87H155N23O17
Standard
Sequence
NKWKKILGKIIKVVK
Physicochemical Analysis
1795.31 Da
10.70
5.75
5.54
0.3836
-0.17
0.75
-0.08
7.74
142.67
0.0667
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
685.72
-1.31
24.0
23.0
67.0
127.0
2.0
15.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0004287 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
SW480
37 μM
IC50
PaperToxicity study of antimicrobial peptides from wild bee venom and their analogs toward mammalian normal and cancer cells. Peptides. 2012 Jan;33(1):18-26. doi: 10.1016/j.peptides.2011.11.002. PMID: 22100226. PMID22100226 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22100226/
RECORD: Rec_0009135 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
CCRF-CEM
5±3 μM
IC50
PaperToxicity study of antimicrobial peptides from wild bee venom and their analogs toward mammalian normal and cancer cells. Peptides. 2012 Jan;33(1):18-26. doi: 10.1016/j.peptides.2011.11.002. PMID: 22100226. PMID22100226 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22100226/
RECORD: Rec_0042587 VERIFIED: YES
Provenance & Taxonomy
Lasioglossum laticeps [Animal]
Lasioglossin III
88510.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Anticancer Antimicrobial Antifungal
HeLa (cervical cancer)
5 ± 2 μM
IC50
PaperToxicity study of antimicrobial peptides from wild bee venom and their analogs toward mammalian normal and cancer cells | https://pubmed.ncbi.nlm.nih.gov/22100226/ PMID22100226 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22100226/
RECORD: Rec_0123466 VERIFIED: YES
Provenance & Taxonomy
Insecta [Animal]
50557
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperToxicity study of antimicrobial peptides from wild bee venom and their analogs toward mammalian normal and cancer cells PMID22100226 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22100226/
RECORD: Rec_0137225 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
PaperCancerPPD: a database of anticancer peptides and proteins PMID25270878 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25270878/
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