Peptide Database

Peptide NameLeukemia inhibitory factor

Function Ontology

Immunology ▸ Immune modulation ▸ Cytokine modulation

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Angiogenic

Standard StatusStandard

Sequence Length180 amino acids

Chemical FormulaC884H1415N245O251S7

DescriptionStandard

        SPLPITPVNATCAIRHPCHNNLMNQIRSQLAQLNGSANALFILYYTAQGEPFPNNLDKLCGPNVTDFPPFHANGTEKAKLVELYRIVVYLGTSLGNITRDQKILNPSALSLHSKLNATADILRGLLSNVLCRLCSKYHVGHVDVTYGPDTSGKDVFQKKKLGCQLLGKYKQIIAVLAQAF
    

Molecular Weight19715.64 Da

Isoelectric Point (pI)9.28

Net Charge (pH 7.0)7.92

Net Charge (pH 7.4) 7.28

Charge Density (pH 7.0) 0.0440

GRAVY Index-0.06

Hydrophobic Moment 0.58

Boman Index0.08

Instability Index23.71

Aliphatic Index 101.33

Aromaticity 0.0722

Extinction Coeff. Reduced 10430.00

Extinction Coeff. Oxidized 10805.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7941.53

LogP -91.35

H-bond Donors 272.0

H-bond Acceptors 272.0

Rotatable Bonds 646.0

Heavy Atoms 1387.0

Ring Count 30.0

Amide Bonds 202.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0230240 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyLIF/OSM family

Tax ID9606; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide12-134; 18-131; 60-163

Bio-Activity Profile

Function

Cytokine Growth factor LIF OSM family Growth factor signaling Angiogenic