Peptide Database

Peptide NamePeptide 46

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length19 amino acids

Chemical FormulaC111H180N36O21

DescriptionStandard

        RPKKPRPYLPFPRPPRPVR
    

Molecular Weight2354.85 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)6.76

Net Charge (pH 7.4) 6.55

Charge Density (pH 7.0) 0.3556

GRAVY Index-1.77

Hydrophobic Moment 0.63

Boman Index-0.58

Instability Index84.83

Aliphatic Index 35.79

Aromaticity 0.1053

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 898.57

LogP -5.36

H-bond Donors 30.0

H-bond Acceptors 28.0

Rotatable Bonds 64.0

Heavy Atoms 168.0

Ring Count 10.0

Amide Bonds 18.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0201908 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-Term1-Amino cyclohexyl carboxylic acid

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetStaphylococcus aureus DSM 6247

Activity32 μg/mL

MethodMIC

RECORD: Rec_0368664 VERIFIED: YES