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MYP_054309
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
4 amino acids
C27H38N6O6
Standard
Sequence
WIQP
Physicochemical Analysis
542.63 Da
5.53
-0.24
-0.44
-0.0600
-0.38
0.53
0.36
55.65
97.50
0.2500
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
200.71
0.39
6.0
6.0
13.0
39.0
3.0
4.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0262846 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antidiabetic DPP-IV inhibitory
Dipeptidyl peptidase IV
237.3
IC50
PaperNongonierma A. B., FitzGerald R. J.. Inhibition of dipeptidyl peptidase IV (DPP-IV) by proline containing casein-derived peptides. J. Funct. Foods, 5, 1909-1917, 2013.
RECORD: Rec_0298789 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
14.2
IC50
PaperNorris R., O¡¯Keeffe M. B., Poyarkov A., FitzGerald R. J.. Peptide identification and angiotensin converting enzyme (ACE) inhibitory activity in prolyl endoproteinase digests of bovine alpha-s-casein. Food Chem., 188, 210-217, 2015.
RECORD: Rec_0337126 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
alpha-S2-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
ACE inhibitory Antihypertensive
Angiotensin-converting enzyme (ACE)
14.2 μM
IC50
PaperPeptide identification and angiotensin converting enzyme (ACE) inhibitory activity in prolyl endoproteinase digests of bovine αs-casein | Norris, R. et al. | DOI: 10.1016/j.foodchem.2015.04.130 Evidence URLhttps://www.uniprot.org/uniprotkb/P02663/entry
RECORD: Rec_0405335 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Casein-derived peptide
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory
Angiotensin-I converting enzyme
14.2±2.9 μM
IC50
RECORD: Rec_0405873 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
alpha-S2-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
DPP-IV inhibitory Antidiabetic
Dipeptidyl peptidase-IV (DPP-IV)
237.3 μM
IC50
PaperInhibition of dipeptidyl peptidase IV (DPP-IV) by proline containing casein-derived peptides | Nongonierma, A. et al. | DOI: 10.1016/j.jff.2013.09.012 Evidence URLhttps://www.uniprot.org/uniprotkb/P02663/entry