Peptide Database

Peptide NameHNH endonuclease

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Nuclease

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length108 amino acids

Chemical FormulaC560H877N165O168S2

DescriptionStandard

        MGAPIPSQIADKLRGRTFNNFDDFRRAFWKEVGNDPELSKQFKRTNQEDMKNSLSPYSPKLEQVGSRQKYEIHHVQFIKDDGSVYGLDNLRVITPKRHIEIHSNKEEK
    

Molecular Weight12673.09 Da

Isoelectric Point (pI)9.22

Net Charge (pH 7.0)2.87

Net Charge (pH 7.4) 2.41

Charge Density (pH 7.0) 0.0265

GRAVY Index-1.09

Hydrophobic Moment 0.63

Boman Index-0.25

Instability Index56.31

Aliphatic Index 63.15

Aromaticity 0.0926

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 9970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5476.40

LogP -56.53

H-bond Donors 186.0

H-bond Acceptors 177.0

Rotatable Bonds 433.0

Heavy Atoms 895.0

Ring Count 21.0

Amide Bonds 120.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0185248 VERIFIED: NO

Provenance & Taxonomy

OrganismPhotorhabdus luminescens [Bacterium]

FamilyColicin/Pyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Endonuclease Hydrolase Nuclease Non-hemolytic Non-ribosomal

MethodQualitative functional evidence