Peptide Database

Peptide NametkmA signal peptide

Function Ontology

Annotation / Sequence feature ▸ Signal peptide

Biotechnology / Production and expression ▸ Secretory enzyme production ▸ Cutinase secretion

Biotechnology / Production and expression ▸ Secretory expression optimization

Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC140H251N35O43S2

DescriptionStandard

        MGESTSLKEILSTLTKRILLIMIVTAAATA
    

Molecular Weight3176.83 Da

Isoelectric Point (pI)8.34

Net Charge (pH 7.0)0.50

Net Charge (pH 7.4) 0.28

Charge Density (pH 7.0) 0.0168

GRAVY Index0.89

Hydrophobic Moment 0.59

Boman Index0.28

Instability Index35.21

Aliphatic Index 140.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1257.60

LogP -11.12

H-bond Donors 46.0

H-bond Acceptors 46.0

Rotatable Bonds 110.0

Heavy Atoms 220.0

Ring Count 0.0

Amide Bonds 29.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0338644 VERIFIED: YES

Provenance & Taxonomy

OrganismBacillus subtilis [Bacterium]

FamilySec signal peptide

Tax ID1423

Structure & Mods

Configlinear signal peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Protein secretion signal peptide Secretory expression optimization Cutinase secretion

TargetBacillus subtilis TEB1030

Activity0.0 U/mL

MethodCutinase activity assay

PaperBrockmeier U, Caspers M, Freudl R, et al. Systematic screening of all signal peptides from Bacillus subtilis: A powerful strategy in optimizing heterologous protein secretion in gram-positive bacteria[J]. Journal of Molecular Biology, 2006, 362(3): 393-402. PMID16930615 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16930615/