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MYP_054290
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Basic Information
Bactericidin B-2
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
37 amino acids
C169H276N54O49
Standard
Sequence
WNPFKELERAGQRVRDAVISAAPAVATVGQAAAIARG
Physicochemical Analysis
3848.33 Da
10.67
1.77
1.56
0.0477
0.02
0.87
0.04
19.25
90.00
0.0541
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1664.38
-18.15
58.0
51.0
123.0
272.0
5.0
39.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0308413 VERIFIED: YES
Provenance & Taxonomy
Tobacco hornworm [Animal]; Insecta [Animal]
33208; 50557
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID2777377 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2777377/
RECORD: Rec_0341799 VERIFIED: YES
Provenance & Taxonomy
Manduca sexta [Animal]
Cecropin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PMID3143727 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3143727/
RECORD: Rec_0377504 VERIFIED: NO
Provenance & Taxonomy
Manduca sexta [Animal]
Cecropin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Anti-Gram-negative Anti-Gram-positive Non-hemolytic Non-ribosomal
Gram-negative bacteria; Gram-positive bacteria
Qualitative functional evidence
PMID3143727 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3143727/; https://www.uniprot.org/uniprotkb/P14662/entry; https://bblserver.org.in/ampdb/
RECORD: Rec_0402075 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperDickinson L., Russel V., Dunn P.E.;. "A family of bacteria-regulated, cecropin D-like peptides from Manduca sexta."; J. Biol. Chem. 263:19424-19429. Evidence URLhttps://www.uniprot.org/uniprotkb/CEC2_MANSE/entry
RECORD: Rec_0426569 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Toxic Anti-Gram-positive Cytotoxic Anti-Gram-negative
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
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