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MYP_054290
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Basic Information
Bactericidin B-2
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
37 amino acids
C169H276N54O49
Standard
Sequence
WNPFKELERAGQRVRDAVISAAPAVATVGQAAAIARG
Physicochemical Analysis
3848.33 Da
10.67
1.77
1.56
0.0477
0.02
0.87
0.04
19.25
90.00
0.0541
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1664.38
-18.15
58.0
51.0
123.0
272.0
5.0
39.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0001660 VERIFIED: YES
Provenance & Taxonomy
Tobacco hornworm [Bacterium]
Cecropin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperA family of bacteria-regulated, cecropin D-like peptides from Manduca sexta.
RECORD: Rec_0033699 VERIFIED: YES
Provenance & Taxonomy
Manduca sexta [Animal]
Bactericidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Cytotoxic Anti-mammalian cells
PaperJ. Biol. Chem. 263:19424-19429(1988). | http://www.ncbi.nlm.nih.gov/pubmed/3143727 PMID3143727 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3143727/
RECORD: Rec_0057583 VERIFIED: YES
Provenance & Taxonomy
Manduca sexta [Animal]
Cecropin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperPubMed PMID: 3143727 PMID3143727 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3143727/
RECORD: Rec_0102134 VERIFIED: YES
Provenance & Taxonomy
Manduca sexta [Animal]
7130
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Evidence URLhttps://patents.google.com/patent/US20050260715A1/en PatentUS 2005/0260715 A1
RECORD: Rec_0213348 VERIFIED: NO
Provenance & Taxonomy
Manduca sexta [Animal]
Cecropin
7130
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Lytic
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