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MYP_054280
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Basic Information
Pep27 (Bacteriocin)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
27 amino acids
C139H229N47O40S
Standard
Sequence
MRKEFHNVLSSGQLLADKRPARDYNRK
Physicochemical Analysis
3230.66 Da
10.42
3.59
3.31
0.1329
-1.29
0.70
-0.45
42.79
61.48
0.0741
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1467.33
-15.86
52.0
46.0
112.0
227.0
4.0
29.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0247878 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
RECORD: Rec_0299975 VERIFIED: YES
Provenance & Taxonomy
Streptococcus pneumoniae [Bacterium]
S. pneumoniae
1313
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer
SNU-601
>70 μM
IC50
PMID16004618 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16004618/
RECORD: Rec_0312671 VERIFIED: YES
Provenance & Taxonomy
Streptococcus pneumoniae [Bacterium]
S. pneumoniae
1313
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer
AML-2
MTT/MTS assay
PMID16004618 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16004618/
RECORD: Rec_0362216 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Streptococcus pneumoniae [Synthetic]
Bacteriocin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer
PaperFunctional and structural characteristics of anticancer peptide Pep27 analogues.
RECORD: Rec_0409966 VERIFIED: YES
Provenance & Taxonomy
Streptococcus pneumoniae [Bacterium]
S. pneumoniae
1313
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Cytotoxic
HL-60
>70 μM
IC50
PMID16004618 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16004618/
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