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MYP_054280
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Basic Information
Pep27 (Bacteriocin)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
27 amino acids
C139H229N47O40S
Standard
Sequence
MRKEFHNVLSSGQLLADKRPARDYNRK
Physicochemical Analysis
3230.66 Da
10.42
3.59
3.31
0.1329
-1.29
0.70
-0.45
42.79
61.48
0.0741
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1467.33
-15.86
52.0
46.0
112.0
227.0
4.0
29.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0024282 VERIFIED: YES
Provenance & Taxonomy
Streptococcus pneumoniae [Bacterium]
Bacteriocin
1313
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibacterial Anticancer Antimicrobial
PaperPubMed PMID: 16004618 PMID16004618 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16004618/
RECORD: Rec_0092829 VERIFIED: YES
Provenance & Taxonomy
Streptococcus pneumoniae [Bacterium]
S. pneumoniae
1313
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Cytotoxic
MCF-7
>70 μM
IC50
PMID16004618 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16004618/
RECORD: Rec_0097293 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Anticancer
Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?id=DRAMP00240
RECORD: Rec_0118510 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 14.8%, E 0.0%, T 44.4%, C 40.7% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Antibacterial Antimicrobial Anti-Gram-positive Anti-Gram-negative
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0132184 VERIFIED: YES
Provenance & Taxonomy
Streptococcus pneumoniae [Bacterium]
S. pneumoniae
1313
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Cytotoxic
Jurkat
>70 μM
IC50
PMID16004618 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16004618/
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