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MYP_054275
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Basic Information
Varv peptide H
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
30 amino acids
C125H192N36O43S6
Standard
Sequence
GLPVCGETCFGGTCNTPGCSCETWPVCSRN
Physicochemical Analysis
3079.47 Da
4.53
-1.29
-1.59
-0.0431
-0.02
0.29
0.12
41.26
32.33
0.0667
5500.00
5875.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1240.70
-18.71
48.0
48.0
90.0
210.0
6.0
31.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0215834 VERIFIED: YES
Provenance & Taxonomy
Viola arvensis [Plant]
Defensin
Structure & Mods
side-chain cyclized peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
5-19; 9-21; 14-27
Bio-Activity Profile
Anticancer Cytotoxic
PaperPubMed PMID: 10075760 PMID10075760 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10075760/
RECORD: Rec_0242076 VERIFIED: YES
Provenance & Taxonomy
Viola arvensis [Plant]
Defensin
Structure & Mods
side-chain cyclized peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
5-19; 9-21; 14-27
Bio-Activity Profile
Anticancer Hemolytic
human type O red blood cells
PaperPubMed PMID: 10075760 PMID10075760 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10075760/
RECORD: Rec_0246448 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAntiCP 2.0: an updated model for predicting anticancer peptides (benchmark provenance; exact sequence-level experiment paper unresolved here) | https://pubmed.ncbi.nlm.nih.gov/32770192/
RECORD: Rec_0281437 VERIFIED: YES
Provenance & Taxonomy
Viola arvensis [Plant]
Defensin
Structure & Mods
side-chain cyclized peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
5-19; 9-21; 14-27
Bio-Activity Profile
Anticancer
PaperPubMed PMID: 10075760 PMID10075760 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10075760/
RECORD: Rec_0376441 VERIFIED: YES
Provenance & Taxonomy
Viola arvensis [Plant]; Viola tricolor [Plant]
Cyclotide
214053
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
multiple disulfide bonds reported, sites not specified
Bio-Activity Profile
Anticancer Cytotoxic Enzymatic-degradation Antimicrobial
Human prostate cancer DU145
10 μg/mL
IC50
PaperIsolation and characterization of cytotoxic cyclotides from Viola tricolor | PubMed PMID 10075760 PMID10075760;20580652 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10075760/
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