Peptide Database

Peptide NameLuffin P1c

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antiviral

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxin

Venom / Toxin ▸ Toxin

Standard StatusStandard

Sequence Length43 amino acids

Chemical FormulaC209H355N83O67S4

DescriptionStandard

        GSPRTEYEACRVRCQVAEHGVERQRRCQQVCEKRLREREGRRE
    

Molecular Weight5230.83 Da

Isoelectric Point (pI)9.30

Net Charge (pH 7.0)3.83

Net Charge (pH 7.4) 3.50

Charge Density (pH 7.0) 0.0891

GRAVY Index-1.63

Hydrophobic Moment 0.52

Boman Index-0.69

Instability Index67.66

Aliphatic Index 40.70

Aromaticity 0.0233

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2543.78

LogP -32.12

H-bond Donors 97.0

H-bond Acceptors 76.0

Rotatable Bonds 184.0

Heavy Atoms 363.0

Ring Count 3.0

Amide Bonds 46.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0402958 VERIFIED: YES

Provenance & Taxonomy

OrganismLuffa aegyptiaca [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Disulfide10-31; 14-27

Bio-Activity Profile

Function

Antimicrobial Antiviral Toxin Cytotoxic

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