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MYP_054210
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Basic Information
Neuromedin-B-32
Antiviral
Hormonal / Endocrine ▸ Hormone peptide
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Standard
32 amino acids
C170H255N53O42S
Standard
Sequence
APFNWDLPEPRSRASKIRVHPRGNLWATGHFM
Physicochemical Analysis
3745.24 Da
11.54
2.97
2.68
0.0929
-0.76
0.36
-0.11
38.94
55.00
0.1250
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1514.29
-13.18
53.0
48.0
113.0
266.0
12.0
33.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0044166 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Neuromedin
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antiviral Hormone Endocrine Neuropeptide Neuromodulator Growth regulation Development regulation Myotropic Receptor modulation Immunomodulatory Pruriceptive
expression of the CSF1 receptor
Mammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour
PMID28780306;34133943 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28780306/
RECORD: Rec_0178076 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Neuromedin
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antiviral Hormone Endocrine Neuropeptide Neuromodulator Growth regulation Development regulation Myotropic Receptor modulation Immunomodulatory Pruriceptive
NMBR receptor on dorsal root ganglion neurons
Mammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour
PMID30734045;34133943 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30734045/
RECORD: Rec_0205881 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Neuromedin
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antiviral Hormone Endocrine Neuropeptide Neuromodulator Growth regulation Development regulation Myotropic Receptor modulation Immunomodulatory Pruriceptive
Mammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour
PMID34133943 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34133943/
RECORD: Rec_0238306 VERIFIED: NO
Provenance & Taxonomy
Mus musculus [Animal]
Bombesin/neuromedin-B/ranatensin
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Neuropeptide Hormone
Evidence URLhttps://www.uniprot.org/uniprotkb/NMB_MOUSE/entry
RECORD: Rec_0261572 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Neuromedin
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antiviral Hormone Endocrine Neuropeptide Neuromodulator Growth regulation Development regulation Myotropic Receptor modulation Immunomodulatory Pruriceptive
Leydig cells
Mammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour
PMID34133943 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34133943/
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