Peptide Database

Peptide NamePyosin cloacin_T_dom domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length186 amino acids

Chemical FormulaC959H1475N257O272S2

DescriptionStandard

        MTPIPDGTDTYTTPPFPVPDPKEFNDYILVFPAGSGIKPIYVYLKEDPRKLPGVVTGRGVLLSPGTRWLDMSVSNNGNGAPIPAHIADKLRGREFKTFDEFREALWLEVSQDPELIAQFSSGNQTRIKQGLTAKAPIDGWYYGPKEIVKKFQIHHRVAVEYGGSVYDIDNLRIVTPRLHDEIHYRR
    

Molecular Weight21020.66 Da

Isoelectric Point (pI)6.98

Net Charge (pH 7.0)-0.04

Net Charge (pH 7.4) -0.57

Charge Density (pH 7.0) -0.0002

GRAVY Index-0.46

Hydrophobic Moment 0.54

Boman Index-0.00

Instability Index37.62

Aliphatic Index 81.72

Aromaticity 0.1075

Extinction Coeff. Reduced 29910.00

Extinction Coeff. Oxidized 29910.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8406.72

LogP -90.60

H-bond Donors 286.0

H-bond Acceptors 279.0

Rotatable Bonds 670.0

Heavy Atoms 1490.0

Ring Count 46.0

Amide Bonds 196.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0173747 VERIFIED: YES

Provenance & Taxonomy

OrganismEscherichia coli [Bacterium]

FamilyPyocin/Colicin

Tax ID562

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Hydrolase Non-hemolytic Non-ribosomal

TargetEscherichia coli