Peptide Database

Peptide Name[Sar1, D-Ala12]galanin(1-16)

Function Ontology

Neurological / Signaling ▸ Neuropeptide activity

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length16 amino acids

Chemical FormulaC78H116N20O21

DescriptionStandard

        GWTLNSAGYLLAPHAV
    

Molecular Weight1669.88 Da

Isoelectric Point (pI)6.74

Net Charge (pH 7.0)-0.15

Net Charge (pH 7.4) -0.41

Charge Density (pH 7.0) -0.0096

GRAVY Index0.51

Hydrophobic Moment 0.24

Boman Index0.43

Instability Index14.43

Aliphatic Index 110.00

Aromaticity 0.1250

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 639.28

LogP -4.82

H-bond Donors 22.0

H-bond Acceptors 22.0

Rotatable Bonds 47.0

Heavy Atoms 119.0

Ring Count 5.0

Amide Bonds 16.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0313492 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Bio-Activity Profile

Function

Receptor agonist Neuropeptide activity Signaling peptide

TargetGAL1 receptor (Human); GAL2 receptor (Rat)

Activity0.4 nM

MethodIC50