Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length69 amino acids

Chemical FormulaC332H520N96O100S8

DescriptionStandard

        MEPASPTLYNNPLFRAARGRFKEICAHPNGSCQEFCLETEIQAGRCLNGHACCRPMVFESIIEPTTPKE
    

Molecular Weight7712.78 Da

Isoelectric Point (pI)6.08

Net Charge (pH 7.0)-1.36

Net Charge (pH 7.4) -1.79

Charge Density (pH 7.0) -0.0197

GRAVY Index-0.39

Hydrophobic Moment 0.58

Boman Index-0.04

Instability Index52.37

Aliphatic Index 58.12

Aromaticity 0.0725

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3118.27

LogP -33.46

H-bond Donors 110.0

H-bond Acceptors 109.0

Rotatable Bonds 246.0

Heavy Atoms 536.0

Ring Count 14.0

Amide Bonds 74.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0399197 VERIFIED: NO

Provenance & Taxonomy

OrganismCanis lupus familiaris [Animal]

FamilyDefensin

Tax ID9615

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal