Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length510 amino acids

Chemical FormulaC2484H4023N647O728S21

DescriptionStandard

        MMLLQPDLAGRLQQSDREEDSSDPEKLTAADIKMFLLKCLPLVALIAVAFSANPGVKIRLTQKGLEYGRQLGMASLLEKLKTAQIPDFSGKERVSPIGKVQYSLTNIRVVNLGLPQSALNLVPGSGVQLSITNAFISLHGNWRVKYLRVIKDSGSLDVSVNGLSISQTIAIKSDATGKPEASSASCSASVSSAKVKFHGGASWLYNLFSKFIDKALRKALEKQMCPLVAKSIADLNPRLKTLNVLAKVDKYAEIEYSMVSSPEISQPAIDLNLKGEFYNIGRHQEAPVPAPAFSLPAQSSNMIYIALSSYTPNSAGFVYKNAGVLSMYVTDDMIPRSSPIRLSTSTFGFFIPQISQQFPGLMMKMLVKADKNPVVKFQPNTMTVDATATATAYAIQPNGTLSPLFVLNVETSVSGQMSVSDLKLAGRISLDKMKLTLGTSYVGDFKVNSLDNILQVILKLVVIPTVNVQLSKGYPLPALGSMNLVNTQLQIMQVREGIIFIYCIEFGVSS
    

Molecular Weight55272.78 Da

Isoelectric Point (pI)9.35

Net Charge (pH 7.0)12.74

Net Charge (pH 7.4) 12.20

Charge Density (pH 7.0) 0.0250

GRAVY Index0.13

Hydrophobic Moment 0.85

Boman Index0.13

Instability Index37.50

Aliphatic Index 103.04

Aromaticity 0.0706

Extinction Coeff. Reduced 33350.00

Extinction Coeff. Oxidized 33600.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0422727 VERIFIED: NO

Provenance & Taxonomy

OrganismOryzias melastigma [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria