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MYP_054063
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Basic Information
Unnamed
Anticancer ▸ Apoptosis induction
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ Lipoxygenase Inhibitory
Hemostasis ▸ Antithrombotic activity
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Regulatory peptide ▸ Stimulation activity
Therapeutic / Biomedical activity ▸ Dermatology / Cosmetic bioactivity ▸ Skin aging modulation ▸ Anti-aging
Therapeutic / Biomedical activity ▸ Protective bioactivity ▸ Cell protection ▸ Cytoprotection
Therapeutic / Biomedical activity ▸ Regenerative medicine ▸ Bone metabolism ▸ Osteoanabolic activity
Wound healing/Regeneration ▸ Wound healing
Standard
7 amino acids
C37H65N9O9
Standard
Sequence
VLPVPQK
Physicochemical Analysis
779.97 Da
8.72
0.73
0.52
0.1047
0.23
0.42
0.16
118.63
138.57
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
289.45
-0.93
8.0
10.0
22.0
55.0
2.0
7.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0301083 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
beta-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Wound healing Nitric oxide-modulating Anti-apoptotic Pro-apoptotic
Fibroblasts
PaperNrf2 dependent antiaging effect of milk derived bioactive peptide in old fibroblasts | Kumar, N. et al. | DOI: 10.1002/jcb.28246 Evidence URLhttps://www.uniprot.org/uniprotkb/P02666/entry
RECORD: Rec_0311012 VERIFIED: NO
Provenance & Taxonomy
Bovine milk [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antioxidant
RECORD: Rec_0313457 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913
Structure & Mods
proteolytic peptide fragment [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
34.2 μg/mL
IC50
PaperEnterococcus faecalis strains from food, environmental, and clinical origin produce ACE-inhibitory peptides and other bioactive peptides during growth in bovine skim milk PMID23845432 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23845432/
RECORD: Rec_0370668 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913
Structure & Mods
proteolytic peptide fragment [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Angiotensin-converting enzyme (ACE)
26.3 μg/mL
IC50
PaperEnterococcus faecalis strains from food, environmental, and clinical origin produce ACE-inhibitory peptides and other bioactive peptides during growth in bovine skim milk PMID23845432 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23845432/
RECORD: Rec_0374113 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Osteoanabolic
Epidermal growth factor receptor
PaperPreparation, identification and screening of anti-osteoporosis milk-derived peptides: intervention effects in osteoporosis rats. Food Bioscience 62:105120 (2024). DOI: 10.1016/j.fbio.2024.105120.
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