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MYP_054063
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Basic Information
Unnamed
Anticancer ▸ Apoptosis induction
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ Lipoxygenase Inhibitory
Hemostasis ▸ Antithrombotic activity
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Regulatory peptide ▸ Stimulation activity
Therapeutic / Biomedical activity ▸ Dermatology / Cosmetic bioactivity ▸ Skin aging modulation ▸ Anti-aging
Therapeutic / Biomedical activity ▸ Protective bioactivity ▸ Cell protection ▸ Cytoprotection
Therapeutic / Biomedical activity ▸ Regenerative medicine ▸ Bone metabolism ▸ Osteoanabolic activity
Wound healing/Regeneration ▸ Wound healing
Standard
7 amino acids
C37H65N9O9
Standard
Sequence
VLPVPQK
Physicochemical Analysis
779.97 Da
8.72
0.73
0.52
0.1047
0.23
0.42
0.16
118.63
138.57
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
289.45
-0.93
8.0
10.0
22.0
55.0
2.0
7.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0266774 VERIFIED: YES
Provenance & Taxonomy
Bubalus bubalis [Animal]
Casein-derived peptide
89462
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anti-aging Wound healing
Skin fibroblasts (In vitro)
Cell viability assay; Cytotoxicity assay; Cell proliferation assay; Western blot; ROS assay; Wound healing assay; Collagen assay; Apoptosis assay
PaperNrf2 dependent antiaging effect of milk-derived bioactive peptide in old fibroblasts PMID30592315 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30592315/
RECORD: Rec_0277415 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Casein-derived peptide
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antioxidant Antimicrobial Antibacterial Enzyme inhibitory Anti-Gram-positive
Staphylococcus aureus
25 μg/mL
MIC
RECORD: Rec_0279064 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
ACE-inhibitory peptide
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperEnterococcus faecalis strains from food, environmental, and clinical origin produce ACE-inhibitory peptides and other bioactive peptides during growth in bovine skim milk. PMID23845432 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23845432/
RECORD: Rec_0286894 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Osteoanabolic
PaperReddi S., Shanmugam V. P., Tanedjeu K. S., Kapila S., Kapila R.. Effect of buffalo casein-derived novel bioactive peptides on osteoblast differentiation. Eur. J. Nutr., 57, 593-605, 2018.
RECORD: Rec_0291708 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913
Structure & Mods
proteolytic peptide fragment [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Angiotensin-converting enzyme (ACE)
16.1 μg/mL
IC50
PaperEnterococcus faecalis strains from food, environmental, and clinical origin produce ACE-inhibitory peptides and other bioactive peptides during growth in bovine skim milk PMID23845432 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23845432/
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