Peptide Database

Peptide NameHepcidin

Function Ontology

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Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC88H145N23O24S8

DescriptionStandard

        ICVFCCGCCYKSKCGICCKT
    

Molecular Weight2165.75 Da

Isoelectric Point (pI)8.51

Net Charge (pH 7.0)2.68

Net Charge (pH 7.4) 2.35

Charge Density (pH 7.0) 0.1338

GRAVY Index1.03

Hydrophobic Moment 0.12

Boman Index0.19

Instability Index1.49

Aliphatic Index 53.50

Aromaticity 0.1000

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 754.97

LogP -7.99

H-bond Donors 35.0

H-bond Acceptors 35.0

Rotatable Bonds 70.0

Heavy Atoms 143.0

Ring Count 2.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0359621 VERIFIED: YES

Provenance & Taxonomy

OrganismEidolon helvum [Animal]

FamilyHepcidin

Structure & Mods

ConfigDNA-encoded linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)