Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length88 amino acids

Chemical FormulaC401H630N108O133S14

DescriptionStandard

        MKTFSVAVAVAIVLTFICLQESSAVSSTEVQELEEPMSNDGAVAAAEEMSEDTWKMPYNNRHKRSPADCRFCCGCCPDMTGCGVCCTF
    

Molecular Weight9540.85 Da

Isoelectric Point (pI)4.48

Net Charge (pH 7.0)-6.48

Net Charge (pH 7.4) -6.90

Charge Density (pH 7.0) -0.0736

GRAVY Index0.05

Hydrophobic Moment 0.41

Boman Index0.07

Instability Index83.11

Aliphatic Index 58.75

Aromaticity 0.0682

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3834.59

LogP -45.10

H-bond Donors 140.0

H-bond Acceptors 142.0

Rotatable Bonds 309.0

Heavy Atoms 656.0

Ring Count 12.0

Amide Bonds 92.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0326117 VERIFIED: NO

Provenance & Taxonomy

OrganismSparus aurata [Animal]

FamilyHepcidin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal