Peptide Database

Peptide NameGremlin-2

Function Ontology

Binding / Molecular interaction ▸ Binding activity

Immunology ▸ Immune modulation ▸ Cytokine modulation

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Standard StatusStandard

Sequence Length147 amino acids

Chemical FormulaC736H1178N222O220S10

DescriptionStandard

        RKNRPAGAIPSPYKDGSSNNSERWHHQIKEVLASSQEALVVTERKYLKSDWCKTQPLRQTVSEEGCRSRTILNRFCYGQCNSFYIPRHVKKEEDSFQSCAFCKPQRVTSVIVELECPGLDPPFRIKKIQKVKHCRCMSVNLSDSDKQ
    

Molecular Weight16977.23 Da

Isoelectric Point (pI)9.30

Net Charge (pH 7.0)10.04

Net Charge (pH 7.4) 9.45

Charge Density (pH 7.0) 0.0683

GRAVY Index-0.80

Hydrophobic Moment 0.63

Boman Index-0.23

Instability Index64.03

Aliphatic Index 62.93

Aromaticity 0.0748

Extinction Coeff. Reduced 16960.00

Extinction Coeff. Oxidized 17460.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7235.09

LogP -81.43

H-bond Donors 260.0

H-bond Acceptors 244.0

Rotatable Bonds 572.0

Heavy Atoms 1188.0

Ring Count 26.0

Amide Bonds 161.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0210304 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyDAN family

Tax ID10090; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide52-102; 66-116; 76-134; 80-136

Bio-Activity Profile

Function

Cytokine Growth factor DAN family Heparin-binding