Peptide Database

Peptide NameTCTP(1-9) S9A subsetution mutant

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length9 amino acids

Chemical FormulaC51H86N12O13S

DescriptionStandard

        MIIYRDLIA
    

Molecular Weight1107.37 Da

Isoelectric Point (pI)5.59

Net Charge (pH 7.0)-0.50

Net Charge (pH 7.4) -0.72

Charge Density (pH 7.0) -0.0555

GRAVY Index1.30

Hydrophobic Moment 0.29

Boman Index0.37

Instability Index-9.90

Aliphatic Index 184.44

Aromaticity 0.1111

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 415.55

LogP -0.08

H-bond Donors 15.0

H-bond Acceptors 14.0

Rotatable Bonds 36.0

Heavy Atoms 77.0

Ring Count 1.0

Amide Bonds 8.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0293203 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyTCTP

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermFluorophore labeling

C-TermAmidation

Other ModsN-term detail: Rhodamine labeling

Bio-Activity Profile

Function

Cell-penetrating peptide

TargetHeLa

MethodFluorescence-based uptake assay

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