Peptide Database

Peptide NameAngiotensin I-converting enzyme inhibitory peptide 12

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length16 amino acids

Chemical FormulaC89H139N27O26

DescriptionStandard

        RFQTIYENENGHIRLL
    

Molecular Weight2003.22 Da

Isoelectric Point (pI)6.76

Net Charge (pH 7.0)-0.15

Net Charge (pH 7.4) -0.41

Charge Density (pH 7.0) -0.0093

GRAVY Index-0.79

Hydrophobic Moment 0.37

Boman Index-0.16

Instability Index22.73

Aliphatic Index 97.50

Aromaticity 0.1250

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 896.63

LogP -7.70

H-bond Donors 31.0

H-bond Acceptors 27.0

Rotatable Bonds 67.0

Heavy Atoms 142.0

Ring Count 3.0

Amide Bonds 18.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0150570 VERIFIED: YES

Provenance & Taxonomy

OrganismLens culinaris [Plant]

FamilyAngiotensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Enzyme inhibitory Antioxidant ACE inhibitory

TargetAngiotensin-I converting enzyme

Activity74.54±0.52 μM

MethodIC50