Peptide Database

Peptide NamePreprocathelicidin antimicrobial peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length127 amino acids

Chemical FormulaC633H1010N178O191S6

DescriptionStandard

        METQRASLSLGRWSLWLLLLGLVLPSASAQALSYREAMLRAVDQLNERSSEAHLYRLLELDPPPYQVEDLGARKPVNFRVKETVCPRSNLQPPEQCDFKENGLVKQCVGTLSLYRSDDPFGLNCNEV
    

Molecular Weight14362.26 Da

Isoelectric Point (pI)5.41

Net Charge (pH 7.0)-2.43

Net Charge (pH 7.4) -2.78

Charge Density (pH 7.0) -0.0191

GRAVY Index-0.33

Hydrophobic Moment 0.65

Boman Index-0.05

Instability Index39.36

Aliphatic Index 94.41

Aromaticity 0.0709

Extinction Coeff. Reduced 16960.00

Extinction Coeff. Oxidized 17210.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5955.26

LogP -58.12

H-bond Donors 207.0

H-bond Acceptors 196.0

Rotatable Bonds 472.0

Heavy Atoms 1008.0

Ring Count 21.0

Amide Bonds 139.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0159453 VERIFIED: NO

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyCathelicidin

Tax ID9913

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal

MethodQualitative functional evidence