Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length123 amino acids

Chemical FormulaC621H952N142O188S5

DescriptionStandard

        MLYFGISEYFFKSASLAYYTAGAFNITIAEELSSYFNVTTETFGSIIPEIAQYYVETRPAMLNLRATAAPMVSLQPDTFTLEIHASMEVLAVLPDSTTQSMFTVNIIANTSASLTIFEQKLIG
    

Molecular Weight13575.36 Da

Isoelectric Point (pI)4.32

Net Charge (pH 7.0)-7.39

Net Charge (pH 7.4) -7.69

Charge Density (pH 7.0) -0.0601

GRAVY Index0.39

Hydrophobic Moment 0.52

Boman Index0.27

Instability Index42.84

Aliphatic Index 95.28

Aromaticity 0.1301

Extinction Coeff. Reduced 10430.00

Extinction Coeff. Oxidized 10430.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5239.79

LogP -46.42

H-bond Donors 181.0

H-bond Acceptors 187.0

Rotatable Bonds 434.0

Heavy Atoms 956.0

Ring Count 22.0

Amide Bonds 131.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0269980 VERIFIED: NO

Provenance & Taxonomy

OrganismChelydra serpentina (Snapping turtle) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria