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MYP_053959
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Basic Information
Lyp-1
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Anticancer ▸ Tumor Homing Peptide
Antimicrobial
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
9 amino acids
C36H67N17O12S2
Standard
Sequence
CGNKRTRGC
Physicochemical Analysis
994.15 Da
9.70
2.74
2.51
0.3044
-1.43
0.30
-0.65
52.56
0.00
0.0000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
509.26
-8.69
21.0
17.0
34.0
67.0
0.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0024495 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
fluorescein
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID15197262 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15197262/
RECORD: Rec_0030274 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Fluorescein/FITC labeling
Amidation
Bio-Activity Profile
Drug Delivery Vehicle Cell-penetrating peptide
PaperCPPsite: a curated database of cell penetrating peptides PMID22403286 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22403286/
RECORD: Rec_0040198 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Anticancer
RECORD: Rec_0064604 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 44.4%, C 55.6% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Drug Delivery Vehicle Tumor Homing Peptide
PaperTumorHoPe: a database of tumor homing peptides PMID22523575 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22523575/
RECORD: Rec_0205919 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Library-derived
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Fluorescein/FITC labeling
Amidation
N-term detail: Labelled with fluoresceine
Bio-Activity Profile
Cell-penetrating peptide
MDA-MB-435 cells
Fluorescence-based uptake assay
PMID15197262 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15197262/
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