‹ ›
MYP_053957
← PREVIOUS NEXT → BACK
Basic Information
Brevinin-1E (4-24) Red
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
21 amino acids
C108H182N28O24S2
Standard
Sequence
LLAGLAANFLPKIFCKITRKC
Physicochemical Analysis
2320.90 Da
9.85
3.74
3.50
0.1780
0.85
0.78
0.22
3.45
125.71
0.0952
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
839.81
-4.18
31.0
30.0
77.0
162.0
3.0
21.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0350908 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0365062 VERIFIED: YES
Provenance & Taxonomy
Rana esculenta [Animal]
Brevinin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Antifungal Anti-Gram-negative
Pseudomonas aeruginosa ATCC 9027
12.5 μg/mL
MIC
PMID9748603 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9748603/
RECORD: Rec_0375184 VERIFIED: YES
Provenance & Taxonomy
Rana esculenta [Animal]
Brevinin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Antifungal Anti-Gram-negative
Fungus: Candida albicans ATCC 36232
6.25 μg/mL
MIC
PMID9748603 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9748603/
RECORD: Rec_0410854 VERIFIED: YES
Provenance & Taxonomy
Rana esculenta [Animal]
Brevinin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Antifungal Anti-Gram-negative
Methicillin resistant Staphylococcus aureus
25 μg/mL
MIC
PMID9748603 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9748603/
RECORD: Rec_0411418 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Mouse erythrocytes
77 μg/mL
Paperhttps://pubmed.ncbi.nlm.nih.gov/9748603/ PMID9748603 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9748603/
FIRST PREV 1 2 3 4 5 NEXT LAST
Showing 5 records on this page · Page 4 of 5