Peptide Database

Peptide NameCircular bacteriocin; circularin A uberolysin family

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC453H738N118O117S

DescriptionStandard

        MRKFISKRRIYLLLLGVVTLTVLLPTTLDSSYLAAQFGISTYASKKIIDIAAGAGSVWAVIAVVGGSAGWGTVILAAAKALIKRYGRAAAASW
    

Molecular Weight9741.49 Da

Isoelectric Point (pI)10.56

Net Charge (pH 7.0)8.49

Net Charge (pH 7.4) 8.26

Charge Density (pH 7.0) 0.0913

GRAVY Index0.79

Hydrophobic Moment 0.66

Boman Index0.30

Instability Index24.08

Aliphatic Index 127.10

Aromaticity 0.0968

Extinction Coeff. Reduced 22460.00

Extinction Coeff. Oxidized 22460.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3726.55

LogP -28.57

H-bond Donors 138.0

H-bond Acceptors 127.0

Rotatable Bonds 318.0

Heavy Atoms 689.0

Ring Count 13.0

Amide Bonds 93.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0011668 VERIFIED: NO

Provenance & Taxonomy

OrganismLigilactobacillus agilis [Bacterium]

FamilyBacteriocin

Tax ID1601

Structure & Mods

Confighead-to-tail cyclic bacteriocin scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsCyclized peptide scaffold annotation

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Non-hemolytic Non-ribosomal