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MYP_053867
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Basic Information
Isracidin
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antiviral
Antiviral ▸ Anti-HIV ▸ Anti-HIV-1
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Standard
23 amino acids
C125H203N39O32
Standard
Sequence
RPKHPIKHQGLPQEVLNENLLRF
Physicochemical Analysis
2764.19 Da
9.99
1.94
1.63
0.0843
-0.99
0.38
-0.21
46.49
97.39
0.0435
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1157.31
-8.93
37.0
36.0
91.0
196.0
6.0
26.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0285310 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Isracidin
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Multifunction
CEM-SS
>36.2 μM
IC50
PaperIdentification of novel human immunodeficiency virus type 1-inhibitory peptides based on the antimicrobial peptide database. PMID20086159 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20086159/
RECORD: Rec_0294509 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
PaperWang G., Watson K. M., Peterkofsky A., Buckheit R. W.. Identification of novel human immunodeficiency virus type 1-inhibitory peptides based on the antimicrobial peptide database. Antimicrob. Agents Chemother., 54, 1343-1346, 2010.
RECORD: Rec_0365381 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antiviral Antimicrobial Anti-Gram-negative
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
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