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MYP_053867
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Basic Information
Isracidin
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antiviral
Antiviral ▸ Anti-HIV ▸ Anti-HIV-1
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Standard
23 amino acids
C125H203N39O32
Standard
Sequence
RPKHPIKHQGLPQEVLNENLLRF
Physicochemical Analysis
2764.19 Da
9.99
1.94
1.63
0.0843
-0.99
0.38
-0.21
46.49
97.39
0.0435
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1157.31
-8.93
37.0
36.0
91.0
196.0
6.0
26.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0006521 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Isracidin
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Immunomodulatory Antibacterial Anti-Gram-negative
Escherichia coli; Cronobacter sakazakii
MIC
PaperAntibacterial and immunostimulating casein-derived substances from milk: Casecidin, isracidin peptides | Lahov, E. et al. | DOI: 10.1016/0278-6915(95)00097-6 Evidence URLhttps://www.uniprot.org/uniprotkb/P02662/entry
RECORD: Rec_0028606 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Isracidin
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli; Cronobacter sakazakii
MIC
PaperAntimicrobial activity of two peptides casecidin 15 and 17, found naturally in bovine colostrum | Birkemo, GA. et al. | DOI: 10.1111/j.1365-2672.2008.03996.x Evidence URLhttps://www.uniprot.org/uniprotkb/P02662/entry
RECORD: Rec_0033830 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Casecidin
9913
Structure & Mods
proteolytic peptide fragment [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Immunomodulatory Antimicrobial Antibacterial
PaperVariability of hydrolysis of β-, αs1-, and αs2-caseins by 10 strains of Streptococcus thermophilus and resulting bioactive peptides; Antibacterial and immunostimulating casein-derived substances from milk: casecidin, isracidin peptides PMID22103626;8603791 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22103626/
RECORD: Rec_0066127 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Casecidin
9913
Structure & Mods
proteolytic peptide fragment [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus
PaperImproved functionality of fermented milk is mediated by the synbiotic interaction between Cudrania tricuspidata leaf extract and Lactobacillus gasseri strains; Antibacterial and immunostimulating casein-derived substances from milk: casecidin, isracidin peptides PMID26996626;8603791 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26996626/
RECORD: Rec_0066880 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913
Structure & Mods
proteolytic peptide fragment [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
PaperCharacterization of the microbial diversity and chemical composition of Gouda cheese made by potential probiotic strains as an adjunct starter culture PMID27606488 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27606488/
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