Peptide Database

Peptide NameVenom-like beta-defensin (DefB-vL) (Defensin-BvL) (OaDefB-vL) (Intermediate defensin-like peptide) (Int-DLP) (Ornithorhynchus venom defensin-like peptide) (OvDLP)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length68 amino acids

Chemical FormulaC314H538N110O84S8

DescriptionStandard

        MRLLILFLAVVTLLSLAGPGSAEVRRRRRRPPCEDVNGQCQPRGNPCLRLRGACPRGSRCCMPTVAAH
    

Molecular Weight7454.84 Da

Isoelectric Point (pI)11.31

Net Charge (pH 7.0)8.53

Net Charge (pH 7.4) 8.18

Charge Density (pH 7.0) 0.1255

GRAVY Index-0.10

Hydrophobic Moment 0.57

Boman Index-0.13

Instability Index78.88

Aliphatic Index 87.50

Aromaticity 0.0147

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3108.38

LogP -35.25

H-bond Donors 117.0

H-bond Acceptors 102.0

Rotatable Bonds 240.0

Heavy Atoms 516.0

Ring Count 9.0

Amide Bonds 71.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0031474 VERIFIED: YES

Provenance & Taxonomy

OrganismOrnithorhynchus anatinus [Animal]

FamilyBeta-defensin; Defensin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetStaphylococcus aureus

RECORD: Rec_0168702 VERIFIED: YES