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MYP_053843
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Basic Information
Pb-CATH1 (120-147)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
28 amino acids
C175H290N50O30
Standard
Sequence
RVKRFKKFFRKIKKGFRKIFKKTKIFIG
Physicochemical Analysis
3574.49 Da
12.00
13.75
13.53
0.4911
-0.70
1.04
-0.37
-5.64
66.07
0.2143
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1377.05
-5.23
52.0
44.0
133.0
255.0
6.0
27.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0346215 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 29213
128 μg/mL
MIC
PMID28630199 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28630199/
RECORD: Rec_0358040 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus ATCC 29213
>128 μg/mL
MIC
PaperGenomewide Analysis of the Antimicrobial Peptides in Python bivittatus and Characterization of Cathelicidins with Potent Antimicrobial Activity and Low Cytotoxicity.
RECORD: Rec_0371861 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Salmonella Typhimurium ATCC 14028
1.5 μg/mL
MIC
PaperGenomewide Analysis of the Antimicrobial Peptides in Python bivittatus and Characterization of Cathelicidins with Potent Antimicrobial Activity and Low Cytotoxicity.
RECORD: Rec_0409455 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
PaperGenomewide Analysis of the Antimicrobial Peptides in Python bivittatus and Characterization of Cathelicidins with Potent Antimicrobial Activity and Low Cytotoxicity. Antimicrob Agents Chemother. 2017 Aug 24;61(9):e00530-17. doi: 10.1128/AAC.00530-17. PMID: 28630199. PMID28630199 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28630199/
RECORD: Rec_0412665 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli ATCC 25922
2 μg/mL
MIC
PMID28630199 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28630199/
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