Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length184 amino acids

Chemical FormulaC929H1419N209O285S9

DescriptionStandard

        QIDDLAEVDYSLSSSPAVFQPFIDLDLKGVVFPAGNYTDSPYMAASITIPDQSDSMLYLAFSEYFFQTSSFAYYTAGAFNVTIAEETCSYFNINTEIFGSIIPEVAKYSVTPYPVMLKLMPTEIPIISLQQDSFMVQIQGSMEVLAILPDSTIQSLFTLNIVANTSISLNIFDQKLMGSLCLNR
    

Molecular Weight20364.02 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-14.24

Net Charge (pH 7.4) -14.51

Charge Density (pH 7.0) -0.0774

GRAVY Index0.33

Hydrophobic Moment 0.55

Boman Index0.25

Instability Index54.12

Aliphatic Index 98.59

Aromaticity 0.1250

Extinction Coeff. Reduced 14900.00

Extinction Coeff. Oxidized 15025.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7832.35

LogP -85.80

H-bond Donors 264.0

H-bond Acceptors 280.0

Rotatable Bonds 652.0

Heavy Atoms 1432.0

Ring Count 34.0

Amide Bonds 201.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0124921 VERIFIED: NO

Provenance & Taxonomy

OrganismCinclus mexicanus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria